Our lab's research involves a variety of studies across a wide range of samples. Learn more by reviewing our current and past research, below. Click on the study name for more specific information and to apply:

Active Studies Currently Enrolling    
Chicago Social Drinking Project (CSDP)    
This is an experimental and longitudinal study of a wide range of drinkers in the Chicagoland area running since March 2004. The aim is to assess responses to several commonly used substances, including stimulants, alcohol and sedatives. The study is currently enrolling participants age 21-35 who drink alcohol at least 4 times per week and is actively obtaining follow-up data via follow-upinterviews about alcohol, tobacco, substance use, moods, and stress levels.  
Mobile Alcohol Response Study (MARS)  
This study examines participants' alcohol use, drinking-related experiences, and effects of alcohol on mood and behavior both in the lab and during assessments completed on a mobile phone in the natural environment. The study is currently enrolling participants age 21-29 who drink alcohol at least 2 times per week who have access to either an IPhone or Android phone to use as part of the study.  
Courage to Quit®    
Courage to Quit® is a stop smoking program developed by Dr. Andrea King and the Respiratory Health Association (RHA). The progam is now offered in a "rolling group" format (patients can join anytime) at the University of Chicago Medicine.  The program is consistent with proven, evidence-based smoking cessation methods, including behavioral skills, cognitive skills, and medication information.  

Active Studies Not Currently Enrolling    
Chicago Young Adult Health Study (CYAH)  
The study examines the health characteristics and response to common substances (like alcohol, cigarettes, caffeine, sedatives, etc.) of young adults in the Chicago area. Participation includes answering questionnaires both in and outside of the laboratory environment and attending brief health feedback and assessments sessions followed by follow-up interviews. Enrollment for this study is temporariliy halted.  
Mood, Behaviors, and Social Interactions Project (MBSI)  
This study examines the mood and behavior responses in young adults with a variety of smoking and drinking patterns while completing common tasks (like eating, drinking, smoking, conversing, or viewing pictures) and social interaction. Enrollment for this study is temporarily halted.  

Past Studies    
Hormones and Mood (HAM) Study: 2011-2012  
The HAM study is a scientific research study that examines mood and hormonal responses to naltrexone, an FDA approved drug that is generally utilized in the treatment of opioid and alcohol dependence. We are interested in how naturally occurring levels of certain hormones, such as estrogen, progesterone, or testosterone may affect response to this drug. Therefore, we are studying healthy women at various stages in their menstrual cycle, as well as healthy men. The study involved participation in two laboratory sessions over one to two months at the Clinical Addictions Research Laboratory at the University of Chicago.  
Drinking and Smoking Study (DASS): 2011    
The purpose of this study was to examine different methods of assessing drinking and smoking patterns. Participants were asked to answer questions about their drinking and smoking patterns, either by telephone or online. After being accepted for the study, participants completed two surveys within 3 to 7 days time. Enrollment for this study took place between February and June 2011.  
Online Timeline Followback (O-TLFB) Calendar:  
The DASS Study resulted in the creation and validation of a self-report, online, past month assessment of drinking and smoking behavior via a Timeline Followback interview.

Link to Online Timeline Followback (O-TLFB): OTLFB Code
Chicago STOP Smoking Research Project (C-STOP): 2006-2010  
This study examined the efficacy of an investigational study drug in combination with standard treatment of a nicotine patch and behavioral counseling on quit rates in a stop-smoking trial. The study enrolled subjects from June 2006 to March 2009. All data has been obtained for this study and data is being analyzed for manuscript preparation.  
Social Smoking Moods and Behaviors (SSMB) Study: 2006-2007  
This laboratory study examined the cognitive and mood effects of several classes of substances, such as alcohol, stimulants and sedatives. Social smokers (those who are not nicotine dependent) engaged in two laboratory sessions where they may smoke one or more cigarettes. Subjects completed study measures at various intervals in the sessions.  
Social Smoking Brain Imaging (SSBI) Project: 2006-2007    
In this study, we used a non-invasive, advanced brain imaging technology of functional Magnetic Resonance Imaging (fMRI) to examine specific brain regions associated with social smokers' cognitive and mood effects of alcohol, stimulants or sedatives. Subjects viewed images on a small screen and provided subjective reports and breath tests at several intervals.  

Additional Research Study Opportunities    
Click on the following links to explore additional research opportunities at the University of Chicago outside of the Clinical Addictions Research Laboratory:  
Human Behavioral Pharmacology Laboratory (HBPL) - Harriet de Wit, P.I.  
The HBPL investigates the determinants and the consequences of drug and alcohol use by measuring physiological, behavioral and subjective effects of acute doses of psychoactive drugs in human volunteers.  
Clinical Neuroscience & Psychopharmacology Research Unit (CNPRU) - Emil F. Cocarro, Director  
The CNPRU is a clinical research group in the University of Chicago's Department of Psychiatry. Directed by Emil F. Coccaro, MD, the CNPRU offers clinical trials for people who are experiencing difficulty in their lives in areas such as problems with anger, depression and anxiety.  
Addictive, Compulsive and Impulsive Disorders Research Program - Jon Grant, P.I.    
The Addictive, Compulsive and Impulsive Disorders (ACID) research/clinical group has a variety of treatment services and clinical trial opportunities available in the areas of substance addiction, impulse control, and obsessive compulsive disorder.  


Clinical Addictions Research Laboratory
c/o Dr. Andrea King
University of Chicago
5841 S Maryland Ave
Rm L470, MC3077
Chicago, IL 60637
(773) 834.3878